Our Team

Cristina Zivko

PhD student

"Lipid-based therapeutics for liver fibrosis and their impact on extracellular vesicles"

Aymar Ganguin

PhD student

"Exploiting the potential of bioinspired therapeutics for the treatment of liver diseases"

Gregor Bordon

PhD student

"Biocompatible depot systems for immunomodulatory treatment of patients after vascularized composite allotransplantation"

Marianna Carone

PhD student

"Sustained release formulations for inflammatory bowel disease"

Ivo Skorup

PhD student

"Novel treatments 
for chronic liver diseases"

Sarah Teworte

PhD student

"Localised delivery
for endometrial fibrosis"

Christoph Zimmermann

PhD student

Associated group member in cooperation with Prof. Olivia Merkel, LMU Munich

Simone Aleandri

Senior scientist

Michael Cibien

Master student in 
Molecular Life Sciences, University of Bern

Gina Valentino

Postdoctoral scientist

Adelina Mustafa

Master student in Pharmacy

Despo Chatzikleanthous

Postdoctoral scientist

Rosanne Marxer

Master student in Pharmacy, University of Bern

Adelina Mustafa

Master student in Pharmacy, University of Bern

Cristina Zivko

PhD student

MSc ETH Pharm. Sc, ETH Zurich, Switzerland

Liver fibrosis is the wound-healing response to chronic hepatic insults, often leading to the loss of organ function. It is characterized by the excessive deposition of scar tissue, a process driven by activated hepatic stellate cells (HSC). The broader aim of our research is to assess the impact of lipid-based therapeutics on extracellular vesicles isolated from hepatic cell lines, used as an in vitro model for the progression of liver fibrosis.

This project is in collaboration with Dr. Gregor Fuhrmann, at the Helmholtz-Institute for Pharmaceutical Sciences Saarland (HIPS), Germany.

Aymar Ganguin

PhD student

M. Sc. In Molecular Life Sciences with specifications in Biochemistry and chemical Biology, University of Bern, Switzerland

Gregor Bordon

PhD student

M.Sc. in Industrial Pharmacy & B.E. in Chemical Technology at University of Ljubljana

By transplanting composite grafts such as faces or limbs, vascularised composite transplantation (VCA) has a potential to radically improve patients’ lives. A major challenge is the need for life-long systemic immunomodulatory therapy for these patients, which leads to their shorter life expectancy. My research focuses on building depot delivery systems that bring the drug in the right doses where it’s needed, without doing harm to the other parts of the body. Using biocompatible phospholipids and gels to build these delivery systems, the VCA patients could live longer and with less frequent drug administration.

Marianna Carone

PhD student

M. Sc. In Pharmaceutical Chemistry and Technology, University of Urbino Carlo Bo, Italy

 

Inflammatory bowel disease is a chronic condition of unknown origin characterized by severe inflammation and mucosal destruction in the intestine. There are two main forms: Crohns disease, which can affect the entire gastrointestinal tract; and ulcerative colitis, which is a mucosal inflammation involving the rectum and colon. Biological therapies and small-molecule drug had a clear impact on the management of IBD, however optimization of medical therapy is still required. The broader aim of our research is to build drug delivery systems able to overcome current limitations using biocompatible phospholipids and hydrogels.

Ivo Skorup

PhD student

M. Sc. In Pharmacy, University of Trieste, Italy

M.Sc. in Neuroscience, University of Trieste, Italy

Sarah Teworte

PhD student

M. Eng. (Hons) Chemical Engineering, University of Edinburgh, Scotland, UK

 

Endometriosis is a chronic disease that is estimated to affect around one in ten women of reproductive age. It is characterized by scarring and fibrosis of reproductive organs and surrounding tissue. Despite endometriosis being common, there are few treatment options available. In line with internationally recognized priorities for endometriosis research, our motivation is to develop a treatment that prevents the growth and proliferation of endometriotic lesions.

Christoph Zimmermann

PhD student

Pharmacist (state examination), Ludwig-Maximilians-University Munich, Germany
B.Sc. Management and Technology, Technical University Munich, Germany

My research studies the microfluidic assembly of siRNA embedded nanoparticles to treat allergic asthma. It is in cooperation with Prof O. Merkel at the department of pharmaceutical technology at the LMU Munich.
My everyday motivation and the foundation for my research is my belief in helping patients by tackling scientific problems. Furthermore, the PhD is a great opportunity to promote a project independently.

Simone Aleandri

Senior scientist

PhD, Sapienza University of Rome, Italy

Since the beginning of my studies, I have been interested in working at the interface of chemistry and biology. Through the years, I investigated the biophysical characteristics of bio-membrane; their interaction with drugs, proteins, and fluorescent probes. I had the chance to characterize lipid formulations for different purposes and use them as drug carriers systems. My research is now focused predominantly on the development of a lipid based gel delivery systems. These materials exhibit a unique combination of properties: they are biocompatible and able to entrap molecules of various polarities and sizes; they have a soft-gel consistency that enables them to act as depot and thus enhance the epithelium drug permeability achieving exquisite spatial, temporal and dosage control when administered topically or subcutaneously.

https://publons.com/researcher/3189516/simone-aleandri

https://www.researchgate.net/profile/Simone_Aleandri2

Michael Cibien

Master student in Molecular Life Sciences with specifications in Biochemistry and chemical Biology, University of Bern, Switzerland

Gina valentino

PhD in Chemistry and Molecular Sciences, University of Bern, Switzerland

Pharmacist, Università degli Studi della Calabria, Italy

Despo Chatzikleanthous

Ph.D. , University of Strathclyde, Glasgow, UK