MSc ETH Pharm. Sc, ETH Zurich, Switzerland
Liver fibrosis is the wound-healing response to chronic hepatic insults, often leading to the loss of organ function. It is characterized by the excessive deposition of scar tissue, a process driven by activated hepatic stellate cells (HSC). The broader aim of our research is to assess the impact of lipid-based therapeutics on extracellular vesicles isolated from hepatic cell lines, used as an in vitro model for the progression of liver fibrosis.
This project is in collaboration with Dr. Gregor Fuhrmann, at the Helmholtz-Institute for Pharmaceutical Sciences Saarland (HIPS), Germany.
M. Sc. In Molecular Life Sciences with specifications in Biochemistry and chemical Biology, University of Bern, Switzerland
M.Sc. in Industrial Pharmacy & B.E. in Chemical Technology at University of Ljubljana
By transplanting composite grafts such as faces or limbs, vascularised composite transplantation (VCA) has a potential to radically improve patients’ lives. A major challenge is the need for life-long systemic immunomodulatory therapy for these patients, which leads to their shorter life expectancy. My research focuses on building depot delivery systems that bring the drug in the right doses where it’s needed, without doing harm to the other parts of the body. Using biocompatible phospholipids and gels to build these delivery systems, the VCA patients could live longer and with less frequent drug administration.
M. Sc. In Pharmaceutical Chemistry and Technology, University of Urbino Carlo Bo, Italy
Inflammatory bowel disease is a chronic condition of unknown origin characterized by severe inflammation and mucosal destruction in the intestine. There are two main forms: Crohn’s disease, which can affect the entire gastrointestinal tract; and ulcerative colitis, which is a mucosal inflammation involving the rectum and colon. Biological therapies and small-molecule drug had a clear impact on the management of IBD, however optimization of medical therapy is still required. The broader aim of our research is to build drug delivery systems able to overcome current limitations using biocompatible phospholipids and hydrogels.
M. Sc. In Pharmacy, University of Trieste, Italy
M.Sc. in Neuroscience, University of Trieste, Italy
M. Eng. (Hons) Chemical Engineering, University of Edinburgh, Scotland, UK
Pharmacist (state examination), Ludwig-Maximilians-University Munich, Germany
B.Sc. Management and Technology, Technical University Munich, Germany
My research studies the microfluidic assembly of siRNA embedded nanoparticles to treat allergic asthma. It is in cooperation with Prof O. Merkel at the department of pharmaceutical technology at the LMU Munich.
My everyday motivation and the foundation for my research is my belief in helping patients by tackling scientific problems. Furthermore, the PhD is a great opportunity to promote a project independently.
PhD, Sapienza University of Rome, Italy
Since the beginning of my studies, I have been interested in working at the interface of chemistry and biology. Through the years, I investigated the biophysical characteristics of bio-membrane; their interaction with drugs, proteins, and fluorescent probes. I had the chance to characterize lipid formulations for different purposes and use them as drug carriers systems. My research is now focused predominantly on the development of a lipid based gel delivery systems. These materials exhibit a unique combination of properties: they are biocompatible and able to entrap molecules of various polarities and sizes; they have a soft-gel consistency that enables them to act as depot and thus enhance the epithelium drug permeability achieving exquisite spatial, temporal and dosage control when administered topically or subcutaneously.
Master student in Molecular Life Sciences with specifications in Biochemistry and chemical Biology, University of Bern, Switzerland
PhD in Chemistry and Molecular Sciences, University of Bern, Switzerland
Pharmacist, Università degli Studi della Calabria, Italy
Ph.D. , University of Strathclyde, Glasgow, UK